Computer simulations of lung surfactant

Simulations of Surfactant Spreading

Thin liquid films have been studied extensively because of their interesting mathematical behavior (for instance, [2]) and industrial applications. Films under the influence of surfactants, which lower surface tension in the fluid, exhibit spreading and the formation of capillary ridges. In the experiment I am considering, a ring of surfactant is placed in glycerin, which produces radial propag...

Lung surfactant.

Aspects of pulmonary surfactant are reviewed from a biochemical perspective. The major emphasis is on the lipid components of surfactant. Topics reviewed include surfactant composition, cellular and subcellular sites as well as pathways of biosynthesis of phosphatidylcholine, disaturated phosphatidylcholine and phosphatidylglycerol. The surfactant system in the developing fetus and neonate is c...

Dynamic behavior of lung surfactant.

We have previously developed an adsorption-limited model to describe the exchange of lung surfactant and its fractions to and from an air-liquid interface in oscillatory surfactometers. Here we extend this model to allow for diffusion in the liquid phase. Use of the model in conjunction with experimental data in the literature shows that diffusion-limited transport i.s important for characteriz...

Simulations of Surfactant Driven Thin Film Flow

This thesis is intended to fulfill the requirements of the Math and Physics departments at Harvey Mudd College. We begin with a brief introduction to the study of surfactant dynamics followed by some background on the experimental framework our work is related to. We then go through a derivation of the model we use, and explore in depth the nature of the Equation of State (EoS), the relationshi...

Steroids, surfactant and lung disease.